Glutathione
A tripeptide antioxidant naturally produced in every human cell, essential for detoxification, immune support, and cellular defense against oxidative stress, available in high-dose lyophilized form for research. All presented information is based on scientific publications which can be found at the end of product description below.
Product Specifications
Description
All presented information is based on scientific publications which can be found at the end of product description below.
Glutathione (GSH) is a tripeptide composed of glutamate, cysteine, and glycine — the primary intracellular antioxidant defense system in mammalian cells.
Research Highlights
1. Antioxidant Defense — Most abundant non-protein thiol in cells. Neutralizes ROS and regenerates vitamins C and E.
2. Detoxification — Major phase II mechanism via glutathione S-transferases. Critical for hepatic drug metabolism.
3. Immune Function — T-cell activity and NK cell function depend on adequate intracellular GSH concentrations.
4. Mitochondrial Protection — Essential for membrane integrity and electron transport chain function.
5. Skin Health — Investigated for melanin synthesis inhibition and UV protection.
References available upon request.
The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
Research Use Only: The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
🇪🇺 EU & UK Shipped • Free over €300 • 2-5 Business Days
Frequently asked questions
- Glutathione (GSH) is a tripeptide with structure γ-L-Glutamyl-L-cysteinyl-glycine (γ-Glu-Cys-Gly). Molecular formula C₁₀H₁₇N₃O₆S, molecular weight ≈ 307.3 g/mol. The unusual γ-glutamyl bond makes it resistant to most peptidases.
- Each batch is HPLC-verified at ≥99% purity, with the cysteine thiol group quantified to ensure the reduced form (GSH) is supplied. COA included.
- Store lyophilised GSH at -20 °C, sealed and protected from light and moisture — the cysteine thiol is highly susceptible to oxidation. Reconstitute in degassed buffer and minimize air exposure. Add chelators (EDTA) where appropriate to limit metal-catalyzed oxidation.
- Glutathione is the most abundant intracellular antioxidant. It is studied in oxidative stress models, redox biology, drug detoxification (Phase II conjugation), and as a substrate for glutathione peroxidase and S-transferase research.
- Glutathione is sold as a dietary supplement in some jurisdictions but is not an approved therapeutic for any specific medical condition by FDA. The research-grade material from Peptra Labs is supplied for laboratory research only.
