Thymosin Alpha 1
A naturally occurring thymic peptide with well-documented immunomodulatory properties, approved in 35 countries for hepatitis treatment and investigated for sepsis, cancer, cystic fibrosis, and viral infections. All presented information is based on scientific publications which can be found at the end of product description below.
Product Specifications
Description
All presented information is based on scientific publications which can be found at the end of product description below.
Thymosin Alpha-1 (Tα1/Zadaxin) is a 28-amino-acid peptide naturally produced in the thymus gland. First isolated in 1972, it is approved in 35 nations for hepatitis B and C.
Research Highlights
1. Immune Modulation — Acts through Toll-like receptors in dendritic cells, promotes T-cell differentiation, enhances macrophage function.
2. Viral Infections — Reduces morbidity/mortality in sepsis and infections. COVID-19 studies showed reduced mortality and restored immune function.
3. Oncology — Positive effects in melanoma and breast cancer. Anti-pain properties through microglia-mediated cytokine reduction.
4. Cystic Fibrosis — Identified as potential single-molecule therapy.
5. Vaccine Enhancement — Boosts T-cell responses and vaccine efficacy.
References available upon request.
The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
Research Use Only: The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
🇪🇺 EU & UK Shipped • Free over €300 • 2-5 Business Days
Frequently asked questions
- Thymosin Alpha-1 (Tα1) is a 28-amino-acid acetylated peptide naturally occurring in the thymus. Sequence: Ac-SDAAVDTSSEITTKDLKEKKEVVEEAEN. Molecular weight is approximately 3108 Da. Each batch ships with a COA confirming identity by HPLC and mass spectrometry.
- Each batch is HPLC-MS verified at ≥99% purity. The COA records the chromatogram, MS trace, lot, and synthesis date.
- Store the lyophilised vial at -20 °C, sealed and protected from light. Reconstituted solutions should be aliquoted and used promptly; refer to your lab's standard handling protocols.
- Tα1 has been studied in preclinical and clinical research on immune modulation, particularly in T-cell maturation and innate immune response models. It is approved as a medicine in some jurisdictions but supplied here strictly for laboratory research.
- Tα1 has regional regulatory approval as a therapeutic in some countries (e.g., as Zadaxin) but is supplied by Peptra Labs strictly for research use only. Always verify local regulatory and import requirements before use.
