Ipamorelin
The first selective growth hormone secretagogue that stimulates GH release without affecting ACTH, cortisol, or prolactin levels, investigated for bone health, muscle preservation, and gastrointestinal recovery. All presented information is based on scientific publications which can be found at the end of product description below.
Product Specifications
Description
All presented information is based on scientific publications which can be found at the end of product description below.
Ipamorelin is a synthetic pentapeptide derived from GHRP-1 with GHS-R binding efficacy comparable to GHRP-6. Distinguished by remarkable selectivity — stimulates GH without influencing ACTH, cortisol, prolactin, FSH, LH, or TSH.
Research Highlights
1. Glucocorticoid Countermeasures — Co-administration produced four-fold greater periosteal bone formation vs glucocorticoid alone.
2. Bone Mineral Content — Increased tibial and vertebral BMC through larger bone dimensions and cortical area.
3. Muscle Preservation — Decreased nitrogen wasting and improved organ nitrogen content. Reduced hepatic urea synthesis by 20%.
4. Insulin Secretion — Stimulated insulin release from pancreatic tissue in normal and diabetic models.
5. Postoperative Ileus — Clinical trials showed reduced time to first tolerated meal after surgery.
6. Diagnostic Potential — Derivatives explored as PET imaging probes for GHS-R detection.
References available upon request.
The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
Research Use Only: The product is intended for scientific research and development purposes only. Chemical substances shall not be used as a drug, medicine, active substance, medical aid, cosmetic product, a substance for production of a cosmetic product neither for human consumption that is any food or food supplement or otherwise similarly used on humans or animals. Intended only for in-vitro research, such as Receptor-ligand binding studies, Enzyme activity assays, Cell proliferation assays, Cell signaling assays, Epitope mapping, etc.
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Frequently asked questions
- Ipamorelin is a synthetic pentapeptide with sequence Aib-His-D-2-Nal-D-Phe-Lys-NH₂, designed as a selective growth-hormone-releasing peptide (GHRP). Molecular weight is approximately 711.85 Da. Each batch ships with COA confirming purity and identity.
- Each batch is HPLC-MS verified at ≥99% purity. The COA documents chromatogram, MS trace, lot, and synthesis date.
- Store the lyophilised vial at -20 °C, sealed and protected from light. Reconstituted solutions should be aliquoted and stored at 2-8 °C for short-term use or -20 °C for longer-term storage.
- Ipamorelin is studied in preclinical models of growth hormone secretagogue receptor (GHSR1a) pharmacology, ghrelin pathway research, and pituitary cell function. It is one of the most selective GHRPs reported in the research literature.
- No. Ipamorelin is not approved by FDA, EMA, or other major regulators for human or veterinary use. WADA prohibits GHRPs including Ipamorelin under the S2 category. Supplied strictly for laboratory research.
